Premier League 2025/26: Matchday 22 Betting Tips

by Danny
Premier League Matchday 22

After a short break for some FA Cup Third Round action, the Premier League returns this weekend.

A packed schedule awaits us, with matches taking place on Saturday, Sunday and Monday, starting with the Manchester derby at Old Trafford.

Matchday 22 should be a spectacular show, and we have made our sports betting picks for the weekend based on the latest Premier League odds.

And make sure to play our exclusive Pick 6 game before all the action gets underway. Predict the result in six Premier League fixtures to be in with a chance of winning Free Bets.

*All odds are subject to change

Manchester United vs Manchester City: Player to score or assist – Antoine Semenyo @ 2.95

Semenyo could not have asked for a better start to his City career. The Ghanaian forward scored in each of his first two appearances in the cups vs Exeter and Newcastle. Semenyo gives City an extra dimension in forward areas with his ball-carrying ability, power and directness, skills which are sorely needed in a Manchester derby. He also has a fabulous record vs Man Utd from his Bournemouth days, tallying three goals in just four appearances. At such a good price, we are backing Semenyo to prove decisive in a third consecutive match wearing sky blue.

Sunderland to beat Crystal Palace @ 2.69

Sunderland are the sixth-best team in the Premier League this season in terms of home performance, winning five matches and suffering zero defeats. Of course, Palace also sit sixth in the division’s away table with five wins on the road, but Oliver Glasner’s side have been struggling of late. The Eagles are nine matches without a win in all competitions, losing each of the last two top-flight away games. Sunderland are also boosted by the return of key players from AFCON – namely Noah Sadiki – and can make a real mockery of their seemingly high odds here.

Aston Villa vs Everton: Player to score or assist – Morgan Rogers @ 2.15

Rogers is enjoying another magnificent season in a Villa shirt, scoring yet another goal in last Saturday’s 2-1 win at Spurs in the FA Cup Third Round. In 29 appearances across all competitions this season, the England international has tallied eight goals and six assists, a fine record indeed. And with Everton showing signs of defensive frailty in recent weeks, conceding four at home to Brentford and then drawing 1-1 with Wolves, Rogers could enjoy another successful Premier League outing at Villa Park.

Brighton vs Bournemouth: Total goals – Over 2.5 @ 1.47

The Monday Night Football is a South Coast derby which has all the ingredients of a goal-fest. Brighton and Bournemouth are comfortably the highest goal scorers in the bottom half of the Premier League with a combined total of 65 goals, while the Seagulls have kept just one clean sheet in the last five – and the Cherries only one in the previous seven! Furthermore, over 2.5 goals have been scored in the last five meetings, including Bournemouth’s 2-1 win at the Vitality earlier in the campaign.

 

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